Jing L, Zhang Q, Chang Z, et al. - Using network meta-analysis, researchers sought to assess the effectiveness of nonsurgical secondary prophylaxis interventions for esophageal varices (EV) rebleeding in cirrhotic patients. PubMed, Embase, and the Cochrane Library databases look for secondary prophylaxis of EV rebleeding in cirrhosis. A total of 57 randomized controlled trials have been reviewed. TIPS has been more effective in decreasing the incidence of cirrhosis EV rebleeding, rebleeding-related mortality, and overall mortality in cirrhosis. As a secondary prophylaxis intervention for EV in cirrhosis, TIPS is more likely to be recommended.