Liew JW, Ward MM, Reveille JD, et al. - The association of Nonsteroidal anti-inflammatory drug (NSAID) use with incident hypertension was examined in a longitudinal ankylosing spondylitis (AS) cohort. In this prospective cohort study, enrollment of 1,282 patients was done. The analysis included 628 patients who were without baseline hypertension and had at least 1 year of follow up. Among these, 72% were male, the mean age at baseline was 39 ± 13 years, and continuous use of NSAID was reported in 200 patients. Incident hypertension developed in 129 patients on follow-up. As per findings, continuous NSAID use was noted to be associated with a 12% increased risk for the development of incident hypertension, as compared with non-continuous or no NSAID use.