Geense WW, et al. - Because ICU patients suffer from long-lasting physical, mental, and cognitive health impairments, also known as “postintensive care syndrome,” however, there is a lack of an analysis of the efficacy of therapies to avoid or reduce such impairments, researchers evaluated the efficacy of nonpharmacologic interventions. Thirty-six studies, including 10 pilot studies, were included after screening 17,008 articles (n = 5,165 ICU patients). According to this systematic review and meta-analysis, there is limited evidence of the positive effect of diaries and exercise programs on psychological outcomes. Other commonly used nonpharmacologic interventions in daily ICU practice are not supported by conclusive evidence from this meta-analysis despite outcomes favoring the intervention group. Further data from robust intervention studies using standardized outcomes is needed to improve recovery programs for ICU patients.