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Noninvasive prediction of portal pressure with MR elastography and DCE-MRI of the liver and spleen: Preliminary results

Journal of Magnetic Resonance Imaging Apr 21, 2018

Wagner M, et al. - In patients with chronic liver disease who underwent hepatic venous pressure gradient (HVPG) measurement, researchers gauged the diagnostic performance of MR elastography (MRE) and dynamic contrast-enhanced MRI (DCE-MRI) of the liver and spleen for the prediction of portal hypertension (PH) and clinically significant PH, in comparison with a qualitative PH imaging scoring system. Excellent accuracy for diagnosing PH and fair accuracy were yielded through the combination of liver stiffness and perfusion metrics for clinically significant PH. It was inferred that combined MRE and DCE-MRI outperformed qualitative imaging scores for the prediction of PH.
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