Wagner M, et al. - In this IRB-approved prospective study, the researchers evaluated the diagnostic performance of MR elastography (MRE) and dynamic contrast-enhanced MRI (DCE-MRI) of the liver and spleen for the prediction of portal hypertension (PH) and clinically significant PH, in comparison with a qualitative PH imaging scoring system. Participants in the study were 34 patients with chronic liver disease who underwent hepatic venous pressure gradient (HVPG) measurement. The present data indicated that the combination of liver stiffness and perfusion metrics give excellent accuracy for diagnosing PH, and fair accuracy for clinically significant PH. For prediction of PH, combined MRE and DCE-MRI outperformed qualitative imaging scores.