Cardim D, Robba C, Czosnyka M, et al. - Researchers undertook this prospective observational study to examine the link between standard, invasive intracranial pressure monitoring (ICP_i) and noninvasive intracranial pressure (ICP) evaluation applying a simple formula based on transcranial Doppler (TCD)-derived flow velocity (FV) and mean arterial blood pressure values (ICP_TCD). Participants included 100 consecutive traumatic brain injury patients needing invasive ICP monitoring. No correlation was found between ICP_i and ICP_TCD. Wide 95% limits of agreement between ICP_i and ICP_TCD were shown by Bland-Altman analysis. Experts concluded that TCD represents an insufficiently accurate method for the noninvasive evaluation of ICP, applying a formula based on diastolic FV.