Wang J, et al. - In patients with liver cirrhosis, researchers assessed the accuracy of parameters measured using dual-energy spectral computed tomography (LightSpeed CT750 HD) in evaluating portal venous pressure. In this investigation, 45 patients with liver cirrhosis who had percutaneous transhepatic portal vein puncture as part of their treatment for liver disease were recruited. According to stepwise multivariate linear regression analysis, the iodine concentrations of portal vein and hepatic parenchyma during the portal venous phase and the alanine aminotransferase level were found to be independently related to the direct portal venous pressure. Findings suggested that iodine concentrations of the portal vein (IC_PV) values could be a useful tool in noninvasively evaluating the portal venous pressure and identifying clinically significant portal hypertension in liver cirrhosis.