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Noncutaneous and cutaneous cancer risk in patients with atopic dermatitis: A systematic review and meta-analysis

JAMA Dec 18, 2019

Wang L, et al. - In patients with atopic dermatitis (AD) compared with the general population without AD, researchers evaluated the risk of noncutaneous and cutaneous cancers. For this systematic review and meta-analysis, eight population-based cohort studies (n = 5,726,692 candidates) and 48 case-control studies (n = 114,136 candidates) were included. In population-based cohort studies, AD was statistically significantly related to keratinocyte carcinoma (5 studies) and kidney cancer (2 studies), on the other hand, case-control studies showed lower odds of lung and respiratory system cancers (4 studies). Overall, the authors concluded that potential connections were found between AD and increased risk of keratinocyte carcinoma and kidney cancer as well as lower odds of lung and respiratory system cancers.
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