Ma K, et al. - In this study including a development cohort as well as a training cohort, nomograms for predicting overall survival (OS) and cancer-specific survival (CSS) in patients with surgically resected intrahepatic cholangiocarcinoma (ICC) were constructed and validated. In ICC patients, independent prognostic predictors for OS were age, T stage, M stage, lymph node ratio (LNR) level and tumor grade, while independent prognostic predictors for CSS were T stage, M stage, LNR level and tumor grade. On internal and up to external validation, nomogram predicting OS was with a concordance index (c-index) of 0.751 and 0.725, respectively, and nomogram for CSS was with a c-index of 0.736 and 0.718, respectively. Findings revealed good performance displayed by the developed nomograms for predicting OS and CSS. Also, the possible efficacy of these for prognostic assessment and optimization of individual treatment strategies in ICC patients post-surgery in clinical practice, was suggested.