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Nocturnal excretion in healthy older women and rationale for a safer approach to sleep disruption

Journal of the American Geriatrics Society Dec 17, 2019

Tyagi S, et al. - Given that current therapies for insomnia fail to address one of its most common causes in older adults: nocturia and its main contributor, nocturnal polyuria (NP), particularly in most of the people without lower urinary tract symptoms (LUTS), therefore, researchers investigated the factors related to nocturia in two groups of such older women and the influence of nocturia on sleep in this secondary analysis of two observational studies. There were 39 women without LUTS who had adequate fluid intake (ie, > 1200 mL urine output/24 h recorded on their diary). These individuals had normal videourodynamic testing, and normal daytime frequency (≤ 7 voids). Findings revealed a very common occurrence of nocturia, NP, and decreased bladder capacity even in healthy older women without LUTS, as well as the link of these with impaired sleep. A larger proportion of 24-hour urine output at night and smaller bladder capacity were documented as two factors that contributed independently to nocturia. Overall, effective management of sleep disruption without resulting in complications of sedative-hypnotics may be achieved by employing currently accessible modalities to address both NP and reduced bladder capacity.
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