Hornstrup BG, et al. - Considering the frequent association of chronic kidney disease (CKD) with a blunted nocturnal blood pressure (BP) decrease and obstructive sleep apnea (OSA), researchers studied the links between nocturnal BP decrease and renal function, the degree of OSA, vasoactive hormones, and renal sodium handling in CKD3-4 patients and healthy age-matched controls. Compared with healthy controls, CKD3-4 patients displayed lower brachial and central nocturnal BP decrease. They identified no association of OSA and eGFR with nondipping in CKD patients or healthy controls. In CKD3-4, nondipping was noted to be correlated with obesity, diabetes, and cardiovascular disease.