Chiaie LD, et al. - The authors aimed to ascertain the frequency of obstetrical adverse events and clinical outcome in infants following antenatal hyperimmune globulin (HIG) treatment for primary cytomegalovirus (CMV) infection in pregnancy. They observed that antenatal HIG treatment was well tolerated and not associated with prematurity or decreased birth weight. Findings thus suggested that on the clinical course of congenital CMV infection, HIG application could have a favorable effect.