Förger F, et al. - Researchers examined whether the disease course in women with rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) is influenced by the discontinuation of tumor necrosis factor inhibitors (TNFi) during pregnancy. The Organization of Teratology Information Specialists Autoimmune Diseases in Pregnancy Project, a prospective cohort study, enrolled 490 pregnant women (397 with RA, 93 with JIA) from the US and Canada. TNFi was discontinued by 122 (24.9%) before gestational week 20; TNFi was received beyond week 20 by 201 (41.0%) women, and TNFi was not received during pregnancy by 167 (34.1%) women. As per findings, in women with RA and JIA who enter pregnancy with well-controlled disease, discontinuation of TNFi before gestational week 20 appears feasible.