Night-time heart rate nondipping: Clinical and prognostic significance in the general population
Journal of Hypertension May 06, 2018
Cuspidi C, et al. - Researchers examined the link between a reduced drop of heart rate (HR) at night with subclinical organ damage and cardiovascular events in individuals enrolled in the Pressioni Monitorate E Loro Associazioni study. In the primary analysis, participants were categorized based on the quartiles of nocturnal HR decrease. For the secondary analyses they were additionally categorized based on nondipping nocturnal HR (defined as a drop in average HR at night lower than 10% compared with day-time values), and into four categories: blood pressure (BP)/HR dipper, BP/HR nondipper, HR dipper/BP nondipper, HR nondipper/BP dipper). A blunted dipping of nocturnal HR was found to be related to preclinical cardiac damage in terms of left atrial enlargement. Moreover, it was found to be predictive of cardiovascular morbidity and mortality in the general population.
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