Chen MG, Yang Y, Yang Q, et al. - Researchers assessed the clinical worth of color and power doppler sonography (CPDS) when integrating it with 99mTc-dimercaptosuccinic acid scintigraphy (DMSA) in evaluation of acute pyelonephritis (APN) in infants. This study involved 79 children with APN, including 52 boys and 27 girls, age range 1 month to 3 years old. A sensitivity of 69.4% and specificity of 38.1% was offered by CPDS. In this cohort of infants with APN, there was poor correlation between abnormalities detected by CPDS and DMSA findings. But highly age-related sensitivity of CPDS was evident, it can serve as a non-invasive helpful instrument for early diagnosis of acute pyelonephritis in infants older than 6 months old.