Bento L, Díaz-López A, Barranco G, et al. - Since the International Prognostic Index (IPI) is the most widely used score for non-Hodgkin lymphoma but lacks the ability to recognise a high-risk population in diffuse large B-cell lymphoma (DLBCL), researchers conducted this retrospective study to produce a readily available ‘userfriendly’ prognostic score using easy to obtain variables, assessing the discriminative ability of the new score in comparison with previously reported ones. The sample consisted of 992 patients with DLBCL treated with R-CHOP. The data presented in this work showed a new prognosis score was created with these variables including age categorized into three groups (0, 1, 2 points); Eastern Cooperative Oncology Group ≥ 3–4 with two; stage III/IV, bulky mass, high B2M, LMR < 2·25 and RDW > 0·96 with one each; for a maximum of 9. It presents a more accurate high-risk assessment and risk discrimination for both PFS and OS compared with R-IPI.