New glycemic metrics and traditional clinical and laboratory profiles of children and adolescents with type 1 diabetes mellitus in an outpatient follow-up
Diabetes Research and Clinical Practice Feb 01, 2021
Rodrigues R, Rossi ICB, Rossi BF, et al. - In the present study, the researchers sought to assess the demographic, clinical, and laboratory data - including traditional (as glycated hemoglobin, HbA1c) and new glycemic metrics (as time in range, TiR) - and the complications present in children and adolescents (CA) in outpatient follow-up, as well as their possible associations. The data from this retrospective observational analysis were collected from the medical history of the CA with T1DM (n = 78) being followed up at the Federal University of Uberlândia Pediatric Endocrinology Service. The average age of the participants was 10.2 years (1-16), most of whom (55%) were male, with a diagnosis time of 4.5 years (1-13), and a BMI of 18 kg/m2. The high values of HbA1c and the amplitude of glycemic variability, the short TiR and the early presence of chronic complications indicate that in this population, the treatment did not achieve its target. The control of diabetes in pediatric patients can be optimized by better education of patients and their families about the disease and greater adherence to intensive insulin treatment.
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