Mazaki J, Katsumata K, Kasahara K, et al. - In order to determine the prognostic value of neutrophil-to-lymphocyte ratio (NLR), a reflector of systemic inflammatory response, long-term oncologic outcomes of Stage II-III colon cancer were investigated using a propensity score analysis. Researchers assessed a total of 375 patients with colon cancer who had radical surgery between 2000 and 2014 at Tokyo Medical University Hospital. Before case matching, lower NLR and higher NLR groups showed no significant differences in terms of overall survival (OS) and relapse-free survival (RFS). However, NLR was noted to be predictive of prognosis both in terms of OS and RFS; 5-year OS rates were 94.5% in the lower NLR group and 87.0% in the higher NLR group; 5-year RFS rates were 87.8% in the lower NLR group and 77.9% in the higher NLR group. Overall findings suggest significant prognostic value of the NLR for advanced colon cancer, especially for left-sided colon cancer.