Edara VV, Hudson WH, Xie X, et al. - The neutralizing-antibody response to 4 variants in infected and vaccinated individuals was compared to ascertain how mutations within the spike protein are correlated with virus neutralization. This study’s findings demonstrate that serum neutralizing antibodies rapidly appear after SARS-CoV-2 infection and vaccination and are maintained for several months. According to the findings, the emergence of SARS-CoV-2 variants has raised concerns about the breadth of neutralizing antibody responses.