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Neuromelanin-sensitive magnetic resonance imaging in disease differentiation for Parkinsonism or neurodegenerative disease affecting the basal ganglia

Parkinsonism & Related Disorders May 16, 2021

Matsuura K, Ii Y, Masayuki M, et al. - In this study, the association between neuromelanin-sensitive magnetic resonance imaging (NMI) and severity of Parkinson’s disease (PD) and related disorders, and thereby establishing the diagnostic utility of NMI for diagnosing neurological diseases was explored. Researchers recruited a total of 591 patients (531 individuals after removal of duplicates) with parkinsonism who had undergone NMI. They examined the contrast ratio of the locus coeruleus and the substantia nigra pars compacta in each patient. The results illustrate that NMI effectively contributes to differentiating neurodegenerative diseases, such as PD and progressive supranuclear palsy.

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