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Neurological cancer is a risk factor for bullous pemphigoid: 11-year population-based cohort study

American Journal of Clinical Dermatology Dec 15, 2019

Wu CY, et al. - Among 8,313 patients with neurological cancer and 33,252 age-, gender-, and index-date-matched controls, researchers studied the risk of subsequent bullous pemphigoid (BP) by obtaining data from the Taiwan National Health Insurance Research Database between 2000 and 2012. According to this nationwide population-based cohort study, BP incidence rates were 37.2 for patients with neurological cancer per 100,000 person-years and 6.8 for controls. Data reported that the crude incidence rate ratio was 5.49. For patients with neurological cancer, the meantime to the occurrence of BP was 4.48 ± 3.40 years. The risk of BP increased significantly by neurological cancer, age per year, and dementia. With a relatively short gap of 4.5 years, neurological cancer raised the risk for subsequent BP by 2.4-fold.
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