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Neuroimaging-informed phenotypes of suicidal behavior: A family history of suicide and the use of a violent suicidal means

Translational Psychiatry Jun 22, 2018

Jollant F, et al. - Researchers sought for neuroimaging-informed phenotypes of suicidal behavior via scanning two independent samples of suicide attempters (n = 17 in Montreal, 32 in Jena), patient controls (n = 26/34), and healthy controls (n = 66/34) with magnetic resonance imaging. In addition, they reviewed the literature and run a GingerALE meta-analysis of 12 structural imaging studies comparing suicide attempters and patient controls with whole-brain analyses (n = 693). Outcomes suggest insignificance of considering suicidal behavior as a whole to gain the insight into the biological substratum and identify biomarkers of suicidal risk. However, a family history of suicide (FHoS) and the choice of a violent suicidal means (VSM) seemed to be associated with what could be considered “neural phenotypes”.
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