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Neuro-radiological features can predict hypopituitarism in primary autoimmune hypophysitis

Pituitary May 27, 2018

Tartaglione T, et al. - Authors sought to correlate primary autoimmune hypophysitis (PAH) neuro-radiological signs to endocrine features and assess their prognostic role. For this analysis, 24 PAH cases were selected and classified according to neuro-radiological signs: in 12 adeno-hypophysitis (AHs), 8 infundibulo-neuro-hypophysitis (INHs) and 4 pan-hypophysitis (PHs). Results of this study suggested that neuro-radiological PAH classification in PH, AH and INH can predict pituitary dysfunction and that some neuro-radiological features, such as the pituitary stalk diameter and the loss of the neuro-pituitary bright spot on T1w images can play a role as a positive prognostic marker of the radiological hypophysitis outcome.
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