Clarke CFM - This study was coordinated to discuss the utilization of neuraxial drug delivery (NDD) for the management of cancer pain, based on recent trials, reviews, and guidelines with a focus on cost analysis. From region to region, the ability to demonstrate the cost effectiveness of NDD was variable. Less expensive externalized systems could pose a viable alternative. No new drugs were found to provide any benefit to conventional medications, with the exception of dexamethasone.