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Neoadjuvant chemotherapy and chemotherapy cycle number: A national multicentre study

Gynecologic Oncology Aug 17, 2017

Altman AD, et al. – Researchers inspected the effects of number of chemotherapy cycles in women with ovarian cancer that were treated with neoadjuvant chemotherapy. In this study of a homogenous cohort of patients with stage IIIC or IV high grade serous cancers who received neoadjuvant chemotherapy (NAC), ≥ 4 cycles of NAC had a worse outcome than < 3 cycles likely due to poor prognostic factors or poor response. As per the investigation, the number of consolidation cycles did not appear to make a difference in overall survival.
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