Seidel D, Diedrich S, Herrle F, et al. - Researchers examined the safety and efficacy of negative pressure wound therapy (NPWT) for subcutaneous abdominal wound healing impairment (SAWHI) after surgery via performing a randomized clinical SAWHI study including 507 adults. Patients with SAWHI after surgery without fascia dehiscence were randomly assigned to the treatment arms: negative pressure wound therapy and conventional wound treatment. In the NPWT arm, closure of wounds was significantly faster and more often (36.1 days for 92 of 256 study participants) compared with conventional wound treatment arm (39.1 days for 54 of 251 participants). Wound-related adverse events were reported in higher number of participants in the NPWT arm (48 of 234) vs the conventional wound treatment arm (27 of 201). Based on these findings, NPWT is an effective treatment alternative to conventional wound treatment for SAWHI after surgery, but it is related with more wound-related adverse events.