Wadström K, et al. - This nested case–control study explored the metabolic features that may predispose to giant cell arteritis (GCA). Researchers distinguished and validated individuals who developed GCA after inclusion in a population-based health survey (the Malmö Preventive Medicine Project; N = 33 346) through a structured review of medical records. They selected four controls for every validated case from the database. This analysis distinguish a sum of 76 cases with a confirmed incident diagnosis of GCA (61% female, 65% biopsy positive, mean age at diagnosis 70 years). The evidence showed that establishment of GCA was correlated with lower fasting blood glucose and lower cholesterol and triglyceride levels at baseline, all adjusted for current smoking, implying that metabolic features predispose to GCA.