Shaheen AA, et al. - In patients with cirrhosis, researchers evaluated readmission rates and hospitalization costs and identified risk factors for 90-day readmission. They conducted a weighted analysis of the 2014 Nationwide Readmission Database to identify US adults with cirrhosis-related complications and to evaluate readmission rates at 30, 60, and 90 days post-index hospitalization. The data presented in this work showed a quarter of patients admitted to cirrhosis-related complications were readmitted within 90 days, which represents a significant economic burden associated with the readmission of this population. Interventions and allocation of resources to reduce the rate of readmission of cirrhotic patients remain critical. The index admission estimate for the weighted cumulative national cost was $1.8 billion vs $0.5 billion for readmission. Ascites, hepatic encephalopathy, and bleeding esophageal varices were the main causes of readmission. Male sex, age < 60 years, having private insurance, having ≥ 3 comorbid conditions, and being discharged against medical advice were independent predictors of 90-day readmissions.