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Nasogastric decompression vs no decompression after pancreaticoduodenectomy: The randomized clinical IPOD trial

JAMA Surgery Sep 22, 2020

Bergeat D, Merdrignac A, Robin F, et al. - Researchers conducted a randomized clinical trial investigating whether the absence of systematic nasogastric decompression with a nasogastric tube after pancreaticoduodenectomy affects the occurrence of postoperative complications. The IPOD study (Impact of the Absence of Nasogastric Decompression After Pancreaticoduodenectomy) was an open-label, prospective, single-center, randomized clinical trial conducted including 111 patients randomized to no NGTD (n = 52) or to NGTD (n = 59). Outcomes suggest no significant difference in postoperative complication occurrence (Clavien-Dindo classification grade II or higher) between systematic nasogastric decompression vs no nasogastric decompression after pancreaticoduodenectomy. Hence, avoiding systematic nasogastric decompression may be considered safe after pancreaticoduodenectomy.

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