Nalbuphine as an adjuvant to 0.25% levobupivacaine in ultrasound-guided supraclavicular block provided prolonged sensory block and similar motor block durations (RCT)
Journal of Anesthesia Jun 01, 2018
Abdelhamid BM, et al. - Researchers assessed the impact of adding 20 mg nalbuphine to 25 ml of 0.25% levobupivacaine in supraclavicular brachial plexus block. Patients scheduled for hand and forearm surgeries with supraclavicular block were randomly allocated to receive 25 ml of 0.5% levobupivacaine + 1 ml normal saline (group L); 25 ml of 0.25% levobupivacaine + 1 ml normal saline (group H); or 25 ml of 0.25% levobupivacaine + 1 ml (20 mg) nalbuphine (group N). For these subjects, onset time and duration of sensory and motor block, and time to first analgesic dose were recorded. They found that prolonged duration of sensory block with similar duration of motor block was achieved with the addition of 20 mg nalbuphine to 25 ml of 0.25% levobupivacaine in supraclavicular block.
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