Das BB, Kohli U, Ramachandran P, et al. - Children who developed probable myopericarditis after vaccination with the Pfizer- BioNTech (BNT162b2) COVID-19 mRNA vaccine, tend to exhibit mild and transient symptoms.

• In most cases (90%), symptoms developed following the second dose of vaccine, and the most common presenting symptom was chest pain (100%).

• After receipt of Pfizer mRNA COVID-19 vaccination, a median duration of 2 days (range: < 1-20 days) was recorded for patients to come to medical attention.

• Plasma troponin concentration was raised in all adolescents.

• Normal cardiac function was evident at presentation in 84%.

• Cardiac magnetic resonance imaging (CMR) revealed late gadolinium enhancement consistent with myopericarditis among 15 of 16 patients (94%) undergoing the investigation.

• Treatment comprised ibuprofen or an equivalent NSAID for symptomatic relief in most cases.

• Symptom resolution occurred within 7 days.