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Myelin content changes in probable Alzheimer's disease and mild cognitive impairment: Associations with age and severity of neuropsychiatric impairment

Journal of Magnetic Resonance Imaging Sep 07, 2017

Kavroulakis E, et al. – This recent study aimed to distinguish markers of regional demyelination in patients with probable Alzheimer's disease (AD) and mild cognitive impairment (MCI) in relation to age and severity of neuropsychiatric impairment. It was revealed that age–related demyelination is correlated with memory impairment (especially in prodromal dementia states) and symptoms of depression in an anatomically specific manner.
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