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Myasthenia gravis as a prognostic marker in patients with thymoma

Journal of Thoracic Disease Jun 07, 2018

Cacho-Diaz B, et al. - Researchers analyzed a retrospective 10-year database of the patients with thymoma treated at a single cancer referral hospital (National Institute of Cancer, Mexico City), to study thymoma patients as well as to elucidate the disparities between those with myasthenia gravis (MG) and those without it. The most frequent presentation of MG patients included ptosis, diplopia, appendicular weakness, dysphonia and dysphagia. Positive Acetylcholine Receptor antibodies were detected in almost all the patients with MG. Although different clinical and autoimmune traits completed the manifestation spectrum of MG in patients with thymoma. No survival differences were found, though the median overall survival demonstrated a trend to be higher among the patients with MG.
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