Stokes A, et al. - This trial dealt with the contemplation of music on sleep-wake cycle (SWC) patterns in late preterm neonates. An increasing post conceptual age (PCA) pattern was elicited via music exposure in active sleep, along with fewer interruptions in quiet sleep. Hence, it could be deduced that music possibly benefited sleep in late preterm infants.

Methods

• The scheme of this research was a masked crossover study.
• It enrolled infants between 32-36 6/7 weeks gestation.
• They were randomized to music exposure either during the first six or last six hours of a 12-hour observation period.
• SWC characteristics were determined by continuous amplitude integrated electroencephalography (aEEG) read by two coders masked to exposure sequence.
• Analysis was carried out in paired comparisons. ANOVA contemplated the effects of music exposure, period and crossover on SWC outcomes: 1) Burdjalov Scores (BS) during active sleep (AS) 2) percent and duration of quiet sleep (QS).

Results

• This study selected 30 infants.
• An inspection was performed of 222 quiet sleep cycles (median seven per patient; range five to 12).
• A link was illustrated between music exposure with higher BS (F= 10.60, p = 0.0019) in active sleep and decreased interruptions during QS.
• The advanced post conceptual age (PCA) SWC pattern during AS was determined to be equivalent to a one-week mean.
• There was no variation in the number, duration and ratio of quiet sleep cycles with music exposure.