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Musculoskeletal pain in individuals with inflammatory bowel disease reflects three distinct profiles

Clinical Journal of Pain Jun 13, 2019

Falling C, et al. - Given that over 70% of individuals with inflammatory bowel disease (IBD) experience pain, with abdominal and musculoskeletal pain representing the most common symptoms, researchers sought for subgroups of musculoskeletal pain in these individuals based on clinical features of pain. In addition, they looked for differences in these subgroups regarding demographics, comorbidity, and IBD characteristics. Performing a cross-sectional online survey on adults with IBD, they identified musculoskeletal pain among 208 of 305 included participants. They characterized the three identified subgroups as “mixed mechanism,” “central mechanism,” and “regional and remission.” The subgroup differed regarding total comorbidity score, osteoarthritis, osteoporosis, depression, anxiety, and chronic fatigue syndrome. For depression and anxiety, identified confounders were sex and age.
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