Godfred-Cato S, Tsang CA, Giovanni J, et al. - Given that multisystem inflammatory syndrome in children (MIS-C), temporally correlated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been identified in infants < 12 months old, researchers conducted this investigation to describe the clinical course, laboratory findings, therapeutics and outcomes among infants diagnosed with MIS-C. Infants of age <12 months with MIS-C were detected via reports to the CDC’s MIS-C national surveillance system. A total of 85 infants with MIS-C were found, with 83 (97.6%) testing positive for SARS-CoV-2 infection at a median age of 7.7 months. The most common signs and symptoms recorded were rashes, diarrhea, and vomiting. Hypotension, pneumonia, and coronary artery dilatation or aneurysm were among the other clinical findings. Laboratory abnormalities involved elevated C-reactive protein, ferritin, d-dimer and fibrinogen. Infants appear to have a milder course of MIS-C than older children, with their illness resolving after hospitalization. The complete clinical picture of MIS-C across the pediatric age spectrum is evolving.