Multiple-biomarkers provide powerful prediction of early acute renal allograft rejection by combination of serum fractalkine, IFN-γ and IP-10
Transplant Immunology Aug 08, 2018
Xu CX, et al. - Researchers tested the presumption that for predicting early acute renal allograft rejection, the combination of circulating fractalkine, IFN-γ and IP-10 might serve as effective biomarkers. This was a retrospective study of 87 patients, divided into an acute rejection group and a non-rejection group. During the first month after transplantation, the combination of fractalkine, IFN-γ, and IP-10 was a powerful predictor of early acute renal allograft rejection. In recipients, the immunologic risk of acute allograft rejection could be stratified with the help of these results.
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