Qi Y, Zhang S, Wei J, et al. - In this retrospective study of 199 people with PSA levels of 4–10 ng/mL, experts produced and approved a radiomics model based on multiparametric MRI in people with PSA levels of 4–10 ng/mL in order to prognosticate PCa preoperatively and decrease avoidable biopsies. Individuals were randomized into the primary (n = 133) and validation (n = 66) cohorts, respectively. In comparison with the clinical-radiological model, on both the primary and validation cohorts, the combined model performed superiorly. Moreover, in contrast with the use of the clinical-radiological model, the use of the combined model to prognosticate PCa could recognize more negative PCa people by 18.4%. Thus, in men with PSA levels of 4–10 ng/mL, the combined model was developed and validated to provide a possible preoperative prognostication of PCa and it might help in treatment decision-making and decrease unnecessary biopsies.