Kriegmair MC, Rother J, Grychtol B, et al. - Experts intended to apply real-time multispectral imaging (rMSI) during urethrocystoscopy to combine different imaging modalities to achieve multiparametric cystoscopy (MPC). They conducted MPC in ten individuals with a diagnosed bladder tumor. They obtained 31 lesions using the rMSI set-up. Histopathology showed malignancy in 27 lesions. In five modalities, all lesions could be visualized simultaneously: WL, enhanced vascular contrast (EVC), blue light fluorescence, protoporphyrin IX fluorescence, and autofluorescence. For the first time, they described the application of rMSI in endourology and they ascertained MPC for detection of BC. In addition, this method provides existing imaging modalities to be combined, and it may significantly increase the detection of bladder cancer.