Lee JW, et al. - The consequences of multimodal treatment, including tandem high-dose chemotherapy (HDCT)/autologous stem cell transplantation (auto-SCT), in children with anaplastic ependymomas were determined. The 5-year overall and event-free survival rates were shown to be 85.1% ± 9.7% and 50.0% ± 13.4%, respectively. Hence, multimodal treatment, including tandem HDCT/auto-SCT, can serve as a feasible option for improving survival in the study group.