Yan Y, et al. - Researchers conducted this retrospective cross-sectional study to identify key en face multimodal imaging features of optic disc drusen (ODD). Participants in the study were 786 patients, aged 10 to 82 years, with diagnostic codes for ODD or the term “optic disc drusen” in clinical notes extracted using natural language processing. According to findings, 38 (61 eyes) of 786 patients had high-quality EDI-OCT and en face multimodal imaging. In the diagnosis of ODD, green-light FAF had the highest sensitivity, whereas blue-light FAF and NIR provided more data on the severity, location, depth, and size of ODD. EDI-OCT can be performed in eyes that are negative on green-light FAF and offers the highest-resolution characterization of the entire optic disc to rule out ODD.