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Multicentric EORTC retrospective study shows efficacy of brentuximab vedotin in mycosis fungoides and Sezary syndrome patients with variable CD30 positivity

British Journal of Dermatology Jun 23, 2021

Papadavid E, Kapniari E, Pappa V, et al. - In the present study, the researchers tested the safety and effectiveness of brentuximab vedotin (BV) in mycosis fungoides (MF)/Sezary syndrome (SS) patients with variable CD30 positivity in the real-life cohort and explore potential predictors. The study included information from 72 MF/SS patients from 9 EORTC (European Organization for Research and Treatment of Cancer) centers. Participants in the study were 72 patients. BV is an effective treatment option for MF/SS patients, including those with variable CD30 positivity, LCT, SS, longer disease duration, and who have been previously treated.

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