van der Weijden BM, Achten NB, Bekhof J, et al. - This study was undertaken to evaluate adherence to the Dutch neonatal early‐onset sepsis (EOS) guidelines, adapted from UK guidance. Researchers also looked at the impact on antibiotic recommendations and duration. Between 1 September 2018 and 1 November 2019, a multicentre, prospective observational cross‐sectional study was carried out in seven hospitals in the Netherlands to include a total of 1,024 neonates born at 32 weeks of gestation or later if they demonstrated at least one EOS risk factor or clinical signs of infection. While some antibiotic use was prolonged despite negative blood cultures, low adherence to the Dutch guidelines meant that the majority of neonates did not receive the antibiotic treatment that was recommended. It is necessary to revise the guidelines.