Terao S, Suzuki S, Yaita H, et al. - While reports of autoimmune gastritis (AIG) are growing with the recent rapid decline in the prevalence of Helicobacter pylori (Hp), researchers in this multicenter registry study have explained AIG's features, especially its endoscopic appearance. Between January 2010 and October 2016, a total of 245 patients (mean age was 67.2 ± 11.4 years) with AIG from 11 institutions in Japan were included and their clinical and endoscopic findings were assessed. Endoscopic examination was the most common approach to diagnose AIG. Repeated incorrect treatment for Hp infection was ranked third among the basis for AIG diagnosis due to a false-positive result in ¹³C-urea breath test. Type 1 neuroendocrine tumor, adenocarcinoma, and hyperplastic polyps are associated with gastric lesions. The most common appearance was corpus pan-atrophy. Remnant oxyntic mucosa, however, was found in 31.5% of the patients. In addition, sticky adherent dense mucus and scattered minute whitish protrusions were noted in nearly 30% of the patients. Data reported that 42.3% of the patients presented with various extents of atrophy despite the prevailing presumption of the antral mucosa remaining normal, and patchy redness and circular wrinkle-like patterns were both noted in about 20% of the patients. The authors believe the study would make it easier to detect possible AIG.