Streur MM, et al. - Researchers investigated common symptoms experienced by patients with implantable cardioverter defibrillators (ICD). Further, they sought for the classes of individuals with alike symptom profiles, reported patient characteristics correlated with distinct symptom profiles, and examined whether outcomes 3 and 12 months post-implant could be predicted with symptom profiles at hospital discharge. They performed secondary analysis of data from a randomized controlled trial comparing Patient+Partner vs Patient-Only interventions intended to help patients manage symptoms, prepare for ICD shocks, and continue daily activities. Among 301 included patients (74% male, mean age 64±11.9 years), they identified three classes: Multi-Symptom (N = 119, 40%), Tired-Rundown (N = 130, 43%), and Mostly Asymptomatic (N = 52, 17%). Relative to patients in other classes, those in the Multi-Symptom class were younger (59.9 years) and reported more anxiety and depression. They identified the lower quality of life and nearly double the rate of hospitalizations after 12 months in correlation to membership in the Multi-Symptom class.