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MRI features of the placenta in fetuses with and without CNS abnormalities

Clinical Radiology Jun 14, 2018

Shapira-Zaltsberg G, et al. - Whether magnetic resonance imaging (MRI) features of the placenta were different in fetuses with and without central nervous system (CNS) abnormalities were examined in this analysis. Researchers analysed fetal MRI of 97 singleton pregnancies retrospectively (19–25 weeks gestation), 65 with CNS morphological abnormalities and 32 controls. Using the Mann–Whitney test, measurements were compared with the presence or absence of CNS fetal abnormalities. Findings revealed that the presence of fetal CNS abnormalities was linked with reduced apparent diffusion coefficient (ADC) values of the placenta. Data reported that placentas of fetuses with CNS abnormalities exhibited a less rapid increase in fetal to placental volume ratio with gestational age (GA). Results suggested that ADC mapping and different growth kinetics of the placenta relative to the fetus could potentially serve as early markers of pathological neurodevelopment.
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