MRI cine-tagging of cardiac-induced motion for noninvasive staging of liver fibrosis
Journal of Magnetic Resonance Imaging Oct 20, 2019
Lefebvre T, Petitclerc L, Hébert M, et al. - In this institutional Review Board-approved two-center prospective study of 76 individuals with chronic liver disease who underwent an MRI cine-tagging examination and a liver biopsy within a 6-week interval, researchers for staging fibrosis in the left liver lobe, assessed the diagnostic performance of MRI cine-tagging, using biopsy as the reference standard. With higher histological fibrosis stage, reduction in liver strain measured on tagged images was noted. Between all fibrosis stages, and between groups of fibrosis stages ≤ F3 vs F4, strain values were significantly distinct. Hence, for measuring liver strain without extra lastography hardware, MRI cine-tagging was concluded to be a favorable procedure. Moreover, to evaluate the left liver lobe, it could be used as a complement to prevailing methods evaluating the right lobe.
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