Panourgias E, et al. - Researchers conducted the study for examining differences in clinical features, MRI findings and tumor biomarker characteristics in screen-detected (SCD) and non-screen detected (NSCD) cancers. By two expert radiologists, 62 women (mean age, 48.4 years; range, 33–68 years) with biopsy confirmed breast cancer who had preoperative breast MRI were retrospectively assessed. They observed that NSCD cancers had a higher prevalence of poor prognostic characteristics in comparison to SCD tumors, including larger tumor size, higher Ki-67 index, and positive nodes. Compared to SCD breast cancers, increased fibroglandular tissue and background parenchymal enhancement (BPE) were strongly related to NSCD cancers and supporting their use as potential MR biomarkers in breast cancer risk models.