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MR diffusion kurtosis imaging for cancer diagnosis: A meta-analysis of the diagnostic accuracy of quantitative kurtosis value and diffusion coefficient

Clinical Imaging Jun 14, 2018

Shen L, et al. - Researchers searched relevant studies in PubMed and Cochrane Library databases and analyzed by Meta-DiSc software to explore the accuracy of diffusion kurtosis imaging (DKI)-derived quantitative parameters (kurtosis values, K; and corrected diffusion coefficients non-Gaussian bias, D) in separating malignant cancers from benign lesions. They involved fourteen eligible studies comprising 1847 lesions in 1107 patients (895 were benign and 952 were malignant). Results obtained from this meta-analysis suggested that DKI ought to be added to the routine imaging protocol for screening cancer, with the highest diagnostic accuracy of diffusion coefficients.
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