Alba AC, Foroutan F, Buchan TA, et al. - Researchers conducted this meta-analysis with the aim to evaluate mortality after veno-arterial extracorporeal membrane oxygenation (V-A ECMO) across multiple etiologies of cardiogenic shock (CS). Of 306 included studies (29,289 patients): 25 were post-heart transplant (771 patients), 13 myocarditis (906 patients), 33 decompensated heart failure ([HF] 3,567 patients), 64 post-cardiotomy (8,231 patients), 10 pulmonary embolism ([PE] 221 patients), 80 acute myocardial infarction ([AMI] 7,774 patients), and 113 post-cardiac arrest ([CA] 7,814 patients). Findings suggest inadequacy of using an overall estimate of mortality for patients with CS requiring V-A ECMO as differential outcomes were evident by etiology.